Study Title:

The Migrating Motor Complex

Study Abstract

The migrating motor complex is a distinct pattern of electromechanical activity observed in gastrointestinal smooth muscle during the periods between meals. It is thought to serve a "housekeeping" role and sweep residual undigested material through the digestive tube. As studied in dogs and man, the cycle recurs every 1.5 to 2 hours and consists of 4 phases:
A period of smooth muscle quiescence lasting 45 to 60 minutes, during which there are only rare action potentials and contractions.
A period of roughly 30 minutes in which peristaltic contractions occur and progressively increase in frequency. Peristalsis originates in the stomach and propagates through the small intestine.
The phase lasting 5 to 15 minutes in which rapid, evenly spaced peristaltic contractions occur. In contrast to the digestive period, the pylorus remains open during these peristaltic contractions, allowing many indigestible materials to pass into the small intestine.
A short period of transition between the barrage of contractions in phase 3 and the inactivity of phase 1.

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