HEALTH NEWS
Study Title:
Mitochondrial biogenesis: An update.
Study Abstract
In response to the energy demand triggered by developmental signals and environmental stressors, the cells launch the mitochondrial biogenesis process. This is a self-renewal route, by which new mitochondria are generated from the ones already existing. Recently, considerable progress has been made in deciphering mitochondrial biogenesis-related proteins and genes that function in health and in pathology-related circumstances. However, an outlook on the intracellular mechanisms shared by the main players that drive mitochondrial biogenesis machinery is still missing. Here, we provide such a view by focusing on the following issues: (a) the role of mitochondrial biogenesis in homeostasis of the mitochondrial mass and function, (b) the signalling pathways beyond the induction/promotion, stimulation and inhibition of mitochondrial biogenesis and (c) the therapeutic applications aiming the repair and regeneration of defective mitochondrial biogenesis (in ageing, metabolic diseases, neurodegeneration and cancer). The review is concluded by the perspectives of mitochondrial medicine and research.
Study Information
J Cell Mol Med. 2020 May;24(9):4892-4899. doi: 10.1111/jcmm.15194. Epub 2020 Apr 12. PMID: 32279443; PMCID: PMC7205802.Full Study
https://pubmed.ncbi.nlm.nih.gov/32279443/Recent News
Behind the Buzz: Alcohol’s Hidden Impact on Gut Health
Quercetin Phytosome & Luteolin: Dynamic Duo for Immune Health and Longevity
Nerve Nutrients for Comfort, Balance, and Neuroprotection
The Power of PEA: Feel Better, Think Sharper, Sleep Deeper
Collagen Peptides and Keratin: Building Blocks for Joints, Bones, and Skin