Study Title:


Study Abstract

Manganese is an essential metal because it is required for proper immune function, regulation of blood sugar and cellular energy, reproduction, digestion, bone growth, blood coagulation, and hemostasis and defense against reactive oxygen species. The beneficial effects of manganese are due to the incorporation of the metal into metalloproteins. The functions carried out by manganese metalloproteins include oxidoreductases, transferases, hydrolases, lyases, isomerases, and ligases. In addition, manganese is incorporated into arginase, glutamine synthetase, phosphoenolpyruvate decarboxylase, pyruvate carboxylase, and manganese superoxide dismutase enzymes. Tissue contents in mammals are in the range of 0.3–2.9 μg Mn/g wet tissue weight (1), making manganese one of the most common metals in tissues.

Study Information

Adv Nutr. 2017 May 15;8(3):520-521. doi: 10.3945/an.117.015305. PMID: 28507016; PMCID: PMC5421128.

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