HEALTH NEWS
Study Title:
Higher blood glucose impairs cardiac autonomic modulation in fasting and after carbohydrate overload in adults.
Study Abstract
This study aimed to assess whether the blood glucose levels influence cardiac autonomic modulation under fasting and after carbohydrate overload conditions. Participants (n = 108) were separated into lower blood glucose and higher blood glucose groups, based on the median (90.5 mg·dL-1) of fasting glucose assessed. The SD2, SDNN, LF indices, and LF/HF increased, and HF decreased after dextrose overload compared with fasting (p < 0.05). Body mass (78.9 vs 69.7 kg), abdominal circumference (90.2 vs 82.2 cm), systolic (113 vs 108 mm Hg) and diastolic (72 vs 67 mm Hg) blood pressure were higher (p < 0.05) in the higher blood glucose group. Heart rate variability (HRV) indices (SD1: 21.0 vs 26.5; SD2: 76.8: vs 86.1; RMSSD: 28.7 vs 37.5; SDNN: 56.1 vs 62.5 ms; pNN50: 10.6 vs 18.9%, HF: 328.4 vs 506.0; LF: 982.8 vs 1259.0 ms2), and the area under the curve of these indices after dextrose overload were lower in the higher blood glucose group (p < 0.05). Additionally, glycemia after dextrose overload was correlated with HRV indices (ρ = -0.216 to -0.273, p < 0.05). Individuals with higher blood glucose, even in the normality range, showed impairment in the cardiac autonomic modulation both at fasting and after carbohydrate overload. Novelty: Higher fasting blood glucose impairs cardiac autonomic modulation. Carbohydrate overload impairs cardiac autonomic modulation.
Study Information
Appl Physiol Nutr Metab. 2021 Mar;46(3):221-228. doi: 10.1139/apnm-2020-0473. Epub 2020 Sep 8. PMID: 32898425.Full Study
https://pubmed.ncbi.nlm.nih.gov/32898425/Recent News
Environmental Toxins Increase Need for Glutathione
Glutathione: Why This Master Antioxidant Is So Important
Colostrum: Liquid Gold for Immunity, Gut Health, and Athletic Recovery
The Hidden Impact: Meds that Deplete Vitamin D and How it Affects Your Health
What’s Your Cellular Age? How Telomeres and Mitochondria Impact Aging