Fiber Reduces Breast Cancer Recurrence
METHODS: Intake of fiber from food and supplements was measured two to three years after breast cancer diagnosis in 493 postmenopausal women from three western states. Concurrently, a fasting blood sample was obtained for assay of estrone, estradiol, free estradiol, testosterone, free testosterone, dehydroepiandrosterone sulfate, sex hormone-binding globulin (SHBG), leptin, C-peptide, insulin-like growth factor-1 (IGF1), and IGF-binding protein-3. Adjusted means of these hormones and peptides were calculated for categories of fiber intake.
RESULTS: High intake of dietary fiber was significantly (P
CONCLUSION: High fiber diets may be beneficial to postmenopausal breast cancer survivors due to fiber's favorable influence on sex hormones and peptides known to affect breast cancer prognosis.
Wayne SJ, Neuhouser ML, Ulrich CM, Koprowski C, Baumgartner KB, Baumgartner RN, McTiernan A, Bernstein L, Ballard-Barbash R.
Dietary fiber is associated with serum sex hormones and insulin-related peptides in postmenopausal breast cancer survivors.
Breast Cancer Res Treat.
New Mexico Tumor Registry, MSC 11 620, 1 University of New Mexico, Albuquerque, NM 87131-0001, USA.