Leptin is a hormone that comes from your fat cells, travels up to your brain, and regulates your metabolism and rate of fat burning and thyroid function. Women have more leptin than men which establishes their naturally higher percentage of body fat. Fat, in turn, helps maintain higher estrogen levels.

Leptin problems cause a disruption in insulin function leading to insulin resistance. Insulin resistance promotes fat to be stored and existing fat not to be broken down or used as fuel, aggravating the estrogen-driven problem of cellulite. Thus, poor diet can lock in the obesity angle and become a major irritant to cellulite, ...