HEALTH NEWS

Study Title:

Effects of Exogenous Phosphatidylserine on Cognitive Functions and Phospholipid Metabolism in the Hippocampus of Aged Rats.

Study Abstract

Administration of exogenous phosphatidylserine to 24-month-old Wistar rats normalized endogenous phosphatidylserine levels in the hippocampus of these aged rats, increasing levels to those seen in young animals. At the same time, feeding of aged rats with phosphatidylserine had no effect on the content or level of synthesis of phosphatidylethanolamine, but promoted increases in the synthesis of phosphatidylcholine without affecting the content of this lipid in the hippocampus of rats aged 24 months. The increases in phosphatidylserine levels seen in the hippocampus in experimental animals due to exogenous lipid was accompanied by increases in the number of active avoidances and decreases in the latent period of avoidances on acquisition of a conditioned reflex in a shuttle box.