Can Carnosine Help Shaky Nerves & Memory?

Byron J. Richards, Board Certified Clinical Nutritionist

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Can Carnosine Help Shaky Nerves & Memory?
Carnosine is an antioxidant that is highly concentrated in your brain, heart, and muscles. A new study shows that it becomes depleted during brain aging1, especially in regions of your brain associated with memory problems (hippocampus) and nerve tremors (substantia nigra).

Upon exposure to stress your brain activates its defense system, which includes a variety of antioxidants. In this research scientists looked into the activation of an enzyme called Carnosinase, which requires carnosine in order to work. The researchers showed that in the aging brain stress increased and antioxidants struggled to keep up. The lower the antioxidants, the worse the brain stress and consequent aging.

One method of coping is to increase carnosinase activity, which eventually depletes carnosine. This is part of the key antioxidant system in your brain that must work properly – which is why carnosine is needed.

While every area of the brain was susceptible to this problem of increased stress and decreased antioxidants, this was especially important to the hippocampus (memory) and substantia nigra (nerve transmission). The substantia nigra is rich in dopamine transmitters and is the area of the brain affected by Parkinson's. To a lesser extent, the shaky extremities that often occur during aging are a clear sign of inadequate antioxidants for the amount of stress an individual is under. Carnosine may be able to help.

Referenced Studies

  1. ^ Carnosine and Brain Aging  Antioxid Redox Signal.   Bellia F, Calabrese V, Guarino F, Cavallaro M, Cornelius C, De Pinto V, Rizzarelli E.

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