Gamma Tocotrienol for Breast Cancer Prevention and Treatment

Monday, October 08, 2012
By: Byron J. Richards,
Board Certified Clinical Nutritionist
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After reviewing the available science and biochemistry on gamma tocotrienol and cancer, researchers from the University of Louisiana at Monroe proclaimed, “The synergistic anti-proliferative and apoptotic effects demonstrated by combined low dose treatment of gamma tocotrienol with other chemotherapeutic agents may provide significant health benefits in the prevention and/or treatment of breast cancer in women, while at the same time avoiding tumor resistance and toxic side effects associated with high dose monotherapy.” It is now becoming widely recognized that various nutrients, including tocotrienols, can not only directly knock out cancer but also help cancer treatments work better.  It is high time the medical community embraces these findings and starts saving lives.

The cancer fighting properties of gamma tocotrienol have been researched for quite some time, as I pointed out in my article, Tocotrienols: Twenty Years of Dazzling Cardiovascular and Cancer Research. Earlier research shows that cancer hijacks the cholesterol synthesis pathway (HMG CoA reductase pathway, also called the melvalonate pathway) to assist its own survival.  While gamma tocotrienol naturally consults this pathway to help lower cholesterol in noncancer situations, scientists realized early on that it behaved quite differently in this pathway in cancer cells – disrupting the pathway and inducing death.  Gamma tocotrienol had intelligence, it helped normal cells survive better while helping kill cancer cells.

In the past few months studies have demonstrated that gamma tocotrienols are a cancer cell’s worst nightmare. They turn on so many gene signals that induce death or weaken the cancer that it is as if the cancer cell is being attacked from every direction.  These new studies show massive cellular damage to cancer cells, disrupted energy production, turning off the blood supply to fuel cancer growth, and the induction of a variety of death signals. They appear especially effective in breast cancer models of cancer. And in every case tested, gamma tocotrienol, while acting as a major poison to cancer cells is nontoxic to normal cells – utterly fascinating.

The practical applications to prevent and assist treatment are obvious, which is why the researchers at the University of Louisiana made such a bold statement.

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