High levels of fat and (n-6) fatty acids in cancellous bone in osteoarthritis
Osteoarthritis (OA) is strongly linked with obesity and patients with osteoporosis (OP) have a low body mass index. Anecdotal evidence, clinical and laboratory, suggests that OA bone contains more fat. However, conversion of osteoblasts to adipocytes is reported in OP and this would suggest that the more porous OP cancellous bone would have a high fat content.
Mandy S Plumb and Richard M Aspden, Department of Orthopaedics, University of Aberdeen, Institute of Medical Sciences, Foresterhill, Aberdeen, AB25 2ZD High levels of fat and (n-6) fatty acids in cancellous bone in osteoarthritis Lipids Health Dis. 2004 June