Study Title:

D-limonene Inhibits Breast Tumor Initiation

Study Abstract

The monocyclic monoterpenoid d-limonene and its source, orange oil, were found to prevent rat mammary carcinomas induced by the direct-acting carcinogen nitrosomethylurea. This chemopreventive effect was limited to the promotion/progression stage in this carcinogenesis model.

Study Information

Maltzman TH, Hurt LM, Elson CE, Tanner MA, Gould MN.
The prevention of nitrosomethylurea-induced mammary tumors by d-limonene and orange oil.
1989 April
Department of Human Oncology, University of Wisconsin-Madison

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