Testosterone Needed for Male Bone Health

Byron J. Richards, Board Certified Clinical Nutritionist

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Testosterone Needed for Male Bone Health
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A rather shocking new study in men undergoing androgen blocking therapy1 as part of prostate cancer treatment found average bone loss of 5% after one year of treatment. The amount of bone loss directly correlated to suppression of testosterone levels. A detailed analysis of bone microarchitecture showed that androgen deprivation therapy seriously disturbs bone architecture, inducing weak bones that are more likely to fracture.

While this study is of importance to men going through prostate cancer treatment it is of importance to all men, as testosterone levels begin to decline at age 40 – an issue known as male andropause. This problem is made worse by an expanding waistline, since we know that high leptin levels (the leptin resistance of obesity) directly suppress testosterone production.

It is currently known that both estrogens and androgens are needed for male bone health. Up until this study researchers believed that estrogen was the most important, although too much or not enough appears to be an equal problem. This is the first study to really shine the light on the value of testosterone for bone health.

I should also point out that the bisphosphonate bone drugs are no solution, and are in fact a major health fraud, as they also disturb bone microarchitecture.
Keeping testosterone levels up as you age and keeping that testosterone behaving in a friendly manner are top priorities for quality of life for any man. I have written extensively on the subject of the androgen receptor in this context. While it takes a little more time to understand health at a “deeper” level, the time is well spent and may mean the difference between quality of health during aging or early death.

Referenced Studies

  1. ^ Androgen Deprivation Causes Unhealthy Bones in Men  Journal of Clinical Endocrinology & Metabolism  1.E. J. Hamilton, A. Ghasem-Zadeh, E. Gianatti, D. Lim-Joon, D. Bolton, R. Zebaze, E. Seeman, J. D. Zajac, M. Grossmann.

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