Pantethine to the Rescue

Byron J. Richards, Board Certified Clinical Nutritionist

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Pantethine to the Rescue
Following a heart attack or a stroke, a low oxygen situation follows (tissue hypoxia) wherein massive free radical damage ensues, driving the severity of the problem. If free radicals could be stopped then damage would be reduced. Researchers looking into this issue came upon a new finding. Activation of the enzyme aldehyde dehydrogenase1 reduced heart attack damage in an experimental model by 60%.

Aldehydes are formed as a result of drinking alcohol. There are many chemicals that have aldehyde bases. The yeast Candida albicans gives off acetaldehyde as a toxic byproduct of its metabolism. And very importantly, when free radicals damage the fatty membranes of cells aldehydes form and as they accumulate they permanently damage cells. Such damage occurs in numerous situations ranging from sunburn, to Parkinson's, and many other problems of wear and tear due to free radical damage.

Normally we think of giving antioxidants to help reduce free radical damage, which is still a valid concept. What is new here is an understanding that significant damage can be prevented by cleaning up the aldehydes. This requires that the enzyme aldehyde dehydrogenase be activated. The researchers were of course trying to find drugs to do this – and of course nature's toolbox already has answers for this problem.

It requires energy in the form of Acetyl-Coenzyme A in order to activate the enzyme aldehyde dehydrogenase, which is readily supplied by the nutrient pantethine. I have use pantethine for many years to help clear the acetaldehyde of alcohol/hangover, the Candida toxins that cause brain fog, and for environmental sensitivity to aldehyde based chemicals like perfumes and nail polish.

This new information gives us a whole new appreciation for this powerful nutrient as a tool to protect cell membranes from free radical damage. This would certainly be important for any health issue of wear and tear, helping to offset the free radical related distress of the issue – no matter what the issue may be.

Referenced Studies

  1. ^ Aldehyde Damage and Heart Attacks  Science  

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