New Study Shows Green Tea Extract Helps Metabolism and Body Clocks

April 24, 2017 | Linda J. Dobberstein, Chiropractor, Board Certified in Clinical Nutrition

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New Study Shows Green Tea Extract Helps Metabolism and Body Clocks
Green tea extract has been consumed for several thousand years. The knowledge of its benefits has been growing over the last few decades. A new ground-breaking study on green tea extract provides strong compelling evidence about its multidimensional benefits beyond what was previously understood. In addition to powerful effects for weight management, green tea extract and its active ingredient EGCG have now been found to synergistically affect some of the most fundamental principles in the body – body clocks and metabolic signaling even in the midst of poor diets.

Sluggish Metabolism is Result of Misbalanced Energy

“Obesity, type 2 diabetes mellitus (T2DM) and the metabolic syndrome are among the most frequent pathological consequences induced by a misbalance of energy homeostasis.” This statement from scientists nearly 10 years ago reflects a growing concern in health today related to diet, modern life 24/7 schedules, and night-time light exposure. A significant piece to this puzzle may have just been found. Modernized societies have seen a ubiquitous explosion of obesity, diabetes, metabolic syndrome and loss of health. In trying to understand what can change it, they discovered a new profound benefit of EGCG and green tea extract and its applications to this loss of energy homeostasis.

In a first-of-its-kind study in Biochim Biophys Acta April 12, 2017, scientists demonstrated that EGCG may ameliorate diet-induced metabolic-circadian rhythm energy disturbances that lead to obesity, diabetes, and metabolic syndrome. This article provoked a lot of excitement in the published scientific literature as it recently was one of the top trending articles on the National Library of Medicine, a worldwide go-to library for medical science.

EGCG Entrains Body Clocks and Gene Signals for Healthy Metabolism

What aroused the attention of scientists in this study pertained to EGCG and its multi-purpose effect on key body organ sites that helped entrain the circadian rhythm, turn on gene signal metabolism and energetic balance, despite high fat, high fructose diets. Scientists used EGCG to see if it could affect Sirt1-PGC1αloop which is part of a metabolic energy-sensing network that regulates energy expenditure. Sirt1-PGC1αloop is involved with SIRT1, AMPK, and mitochondria which are deeply involved with metabolism.

EGCG modulated the Sirt1-PGC1αloop which increased brown fat activity, burned more fatty acids for fuel, and modulated the internal body clocks back to a healthier circadian metabolically active rhythm. Animals fed a high fat, high fructose diet and treated with green tea extract were able to prevent obesity, stop white fat cells from expansion, reduce insulin resistance and help the liver become more metabolically efficient. These metabolic effects occurred because EGCG was able to reset and entrain the circadian clock in the liver and fat tissue, which turned on metabolism. Scientists established that green tea extract helped reorganize and alleviate disrupted metabolism caused by high fat, high fructose diets and disrupted circadian rhythms.

Circadian Rhythms and Why They are So Important

Circadian rhythm chaos is at the crux of numerous metabolic disorders. The loss of the natural internal clock rhythms are influenced by several factors. A high fat and high fructose diet is one powerful factor that causes poor cellular circadian clock rhythms and metabolism by impairing the core clock gene and the clock-controlled gene in the liver and fat cells. There are a number of articles on our site that discuss the innate function of body clocks and how clock disruption affects our health.

Breakthrough on Circadian Rhythms, Aging, & Metabolism

Melatonin Supports Weight Management

Body Clocks and Weight Management – It’s All About Timing

Meal Timing and Composition Affects the Circadian Clock

Disrupted Gut Clocks Linked with IBS, GERD, Obesity, and Other GI Concerns

This new study on green tea extract is powerful for all with shift work, night work, sleep deprivation, erratic schedules, night-time artificial light exposure, and/or those who consume a high fat, high fructose diet and want to stay metabolically fit.

The study points us towards three key principles: healthy circadian rhythms, healthier dietary choices, and the astonishing benefits of green tea extract impact on disrupted metabolism. There are several articles on other green tea extract benefits on our website. Take advantage of the links below to learn more. Green tea extract doses commonly range from 200 mg - 2100 mg or higher per day.

Tips on Fructose

Fructose is in more than just soda pop and high fructose corn syrup. It is found in several fruits, vegetables, and anything with high fructose corn syrup and other foods like fruit juice, applesauce, honey, pears, agave, guava, dried fruit, and watermelon. Two apples or two tablespoons of honey contain the same amount of fructose as one 12 ounce can of soda pop. The goal is to limit or reduce the intake of these foods, especially high fructose corn syrup. Follow The Leptin Diet to help optimize circadian rhythm and dietary choices. On a clinical note, high fructose intake is linked with increased salt-sensitivity, gout, high triglycerides in addition to obesity, type 2 diabetes, and metabolic syndrome.

Green Tea Extract Quality

When choosing a green tea extract supplement, quality is important. Our specially-prepared green tea begins with hand-picking of the leaves to preserve the delicate catechins. We use only the finest quality green tea leaves that are rigorously tested and quality controlled to ensure they are not contaminated with pesticides, heavy metals, or other pollutants that are common in cheap green tea. The polyphenol flavonoids in green tea are known as catechins. The most studied catechin is epigallocatechin gallate (EGCG). Wellness Resources Green Tea Extract is standardized for 70% polyphenols, 60% catechins, and 30% EGCG.*

Remarkable Benefits of Green Tea Extract and EGCG

Several articles on our website discuss the benefits of green tea extract. Like other antioxidants, green tea extract works synergistically with other antioxidants like quercetin, resveratrol, curcumin, silymarin, grape seed extract and omega-3 fish oil. Consider green tea extract with standardized EGCG to improve disrupted circadian rhythms and the challenges of metabolic syndrome. This finding on green tea extract got scientists excited. I hope you are too!

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Green Tea Extracts Lower Total & LDL Cholesterol

Green Tea Flavonoids Protect Arteries

Green Tea and Coffee Reduce the Risk of Stroke

Green Tea Improves Skin Quality in Women, Protects Against UV Radiation

Green Tea Protects Skin from UV Damage

Green Tea Extract Helps Patients with Chronic Lymphocytic Leukemia

Green Tea and Resveratrol Extracts Inhibit Prostate Cancer

Green Tea Polyphenols Enhance Protein Metabolism, Reduce Tumors

Green Tea Protects Against Amyloid Beta Accumulation

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