Mangosteen Reduces Fat Cell Inflammation and Insulin Resistance

Byron J. Richards, Board Certified Clinical Nutritionist

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Mangosteen Reduces Fat Cell Inflammation and Insulin Resistance
A new mangosteen study1 shows that the xanthone antioxidants are able to regulate important gene signals in fat cells, reducing adverse inflammation and insulin resistance (by stabilizing adiponectin levels).

It is now well understood that when you become overweight there is a combination of low grade inflammation, leptin resistance, and insulin resistance. There are many nutrients that help to balance and offset this problem – and mangosteen is one of them.

The xanthones of mangosteen, like tocotrienol vitamin E, are unique in that they are able to readily attach to the inside of cell membranes where they not only act as antioxidants but also as helpful communication regulators of a cell's activities. In this study it was found that mangosteen could favorably influence the key cellular gene signal, NF-kappa B, so that inflammation did not occur. It was also able to stabilize the fat hormone adiponectin – which is vital to preventing insulin resistance.

Referenced Studies

  1. ^ Mangosteen, Fat Cells, Insulin Resistance, and Inflammation  J Nutr.  Akkarach Bumrungpert, Ruchaneekorn W. Kalpravidh, Chureeporn Chitchumroonchokchai, Chia-Chi Chuang, Tiffany West, Arion Kennedy, and Michael McIntosh

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