The Obesity-Leptin Path to Heart Disease

Thursday, November 20, 2008 - Byron Richards, CCN

New research shows that obesity causes heart disease even if the obese person does not have high cholesterol or diabetes.  Using advanced nanosensor technology researchers at Ohio University were able for the first time to pinpoint several mechanisms in humans that link obesity to heart disease.  The findings center around the fat-hormone leptin, which I have written extensively about in several books.

When leptin levels elevate in your blood, which happens when you are overweight, then a chain of events are set in motion that directly increase the risk of heart disease.  The research showed that high levels of leptin resulted in decreased nitric oxide that is required to relax your arteries and enable good blood flow.  At the same time, there was a significant increase in free radical damage due to excess leptin stimulating the production of too much superoxide, in turn reacting with nitric oxide and creating peroxynitrite, a very toxic molecule that disrupts DNA and damages endothelial cells in your circulatory system.

This new study proves conclusively that leptin problems all by themselves, independent of any other cardiovascular health risk issue, have a direct adverse effect on your cardiovascular system that increases the risk for heart disease.  This supports and confirms the earlier research on this topic that I fully cover in The Leptin Diet.

Related Entries: Leptin Problems Cause Disease
Heart Disease Starts At Age 3 in Obese Kids, Doubles the Risk for Early Death
Omega 3 Oils Help Correct Leptin Gene Problems

###

Supplements that support weight management

Other Weight Loss News

View complete Weight Loss News Archives

My cart is empty.   View Cart | Login

• All Health News
• Health News
• Health Tips
• Weight Loss News
• Weight Loss Tips
• Health Freedom News



• The Five Rules of The Leptin Diet®
• What is Leptin?
• Lack of Sleep, Stress, Adrenals, and Obesity
• Zinc, Alcohol Damage, and Thyroid Function
• The Mastering Leptin Lifestyle