Quercetin Helps Correct Fatty Liver and Poor Metabolism

Saturday, December 18, 2010
Byron J. Richards, Board Certified Clinical Nutritionist
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A new animal study with quercetin1 shows that the nutrient can help undo damage caused by a high fat, high cholesterol, and high sugar diet. Not only was fatty liver accumulation reversed, but many factors involved with metabolism were improved including inflammation status, insulin resistance, and problems with lipids (cholesterol and triglycerides).

The accumulation of fat in your liver is a major health turning point in the wrong direction. It correlates directly with your waistline expanding. It means your liver, which is the brain of your body, has become clogged with fatty sludge. This sets the stage for fat to accumulate in all the wrong places all around your body, which is never a good thing.

In the experiment, mice were fed the standard junk food Western diet for 20 weeks at which point they were well on their way to serious metabolic disease, including fatty liver build up.  After 8 weeks on quercetin their livers began to clear out and after 20 weeks they were much better.  Improvement included a boosting of the vital adiponectin Protein hormone that modulates metabolism including glucose and fatty acid catabolism. High levels are associated with low body fat. the prevents insulin resistance, turning off of the gene signals that were laying down excess fat in the liver, and a restoration of the antioxidant/anti-inflammatory defense system that is so often compromised in situations of poor metabolic health.

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Referenced Studies:
  1. ^ Quercetin Improves Fatty Liver and Poor Metabolism  Mol Nutr Food Res  Kobori M, Masumoto S, Akimoto Y, Oike H.

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