Nobiletin and Tangeretin Prevent Insulin Resistance by Improving Fat Fitness

Nobiletin and Tangeretin are citrus-derived polymethoxyflavonoids, uniquely structured flavonoids Plant compound that is associated with pigmentation. Flavonoids have been shown to modify allergens, viruses, inflammation, and various carcinogens. Found in green tea, citrus, berries, onions, parsley, red wine, dark chocolate, and others. that are now shown to directly interact with white adipose tissue in a way that makes your stored fat much healthier, including the prevention of insulin resistance.

The fat cells that are in your white adipose tissue are in a continual state of turnover, meaning that new ones are formed and old ones die off. In an overweight person the new ones are rapidly filled with fat (triglycerides) and quickly become unfit – making it difficult to lose weight and easy to gain weight. In fact, in order to have stable weight loss over time, it is necessary to have a new supply of fat cells that are more metabolically fit. Part of this is not eating too much once you have lost some weight. Cramming your fat cells full is a fast track to getting nowhere fast.

A new study with fat cells shows that nobiletin Type of citrus bioflavonoid shown to have anti-inflammatory, anti-oxidant, and blood sugar support properties. and tangeretin Special type of citrus bioflavonoid shown to reduce the risk for certin cancers, protecting nerve cells, and involved with healthy cholesterol function.¹ have a profound impact on how fat cells develop. The study showed that as baby fat cells matured under the influence of these nutrients, they had less fat in them. Furthermore, the level of adiponectin Protein hormone that modulates metabolism including glucose and fatty acid catabolism. High levels are associated with low body fat. , which prevents insulin resistance, was boosted and the level of another fat cell hormone, resistin, which causes insulin resistance, was decreased. Nobiletin even helped kill off some of the older and more unfit fat cells.

This study is significant because the fitness of your fat is key to managing your body weight and maintaining your cardiovascular health – not to mention preventing type 2 diabetes. An earlier study also showed that these nutrients helped insulin resistance² by decreasing inflammation coming from fat cells. Collectively, these studies show that nobiletin Type of citrus bioflavonoid shown to have anti-inflammatory, anti-oxidant, and blood sugar support properties. and tangeretin Special type of citrus bioflavonoid shown to reduce the risk for certin cancers, protecting nerve cells, and involved with healthy cholesterol function. are novel nutrients that support healthy metabolism by helping to improve the fitness of your fat.