Mangosteen Reduces Fat Cell Inflammation and Insulin Resistance

Thursday, May 21, 2009 - Byron J. Richards, CCN

A new mangosteen study shows that the xanthone antioxidants are able to regulate important gene signals in fat cells, reducing adverse inflammation and insulin resistance (by stabilizing adiponectin levels). 

It is now well understood that when you become overweight there is a combination of low grade inflammation, leptin resistance, and insulin resistance.  There are many nutrients that help to balance and offset this problem – and mangosteen is one of them.

The xanthones of mangosteen, like tocotrienol vitamin E, are unique in that they are able to readily attach to the inside of cell membranes where they not only act as antioxidants but also as helpful communication regulators of a cell’s activities.  In this study it was found that mangosteen could favorably influence the key cellular gene signal, NF-kappa B, so that inflammation did not occur.  It was also able to stabilize the fat hormone adiponectin – which is vital to preventing insulin resistance.

Related Entries: Magnesium Needed for Healthy Adiponectin Levels
Leptin, Adiponectin, and Kidney Disease
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Thyroid Has Company; Insulin Now Found to Impact Temperature
Low Adiponectin Starts Cardiovascular Disease in Motion

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