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Fish Oil Lowers Fat Mass and Shrinks Fat Cells

Monday, December 17, 2007

Byron Richards, CCN


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In a study with 27 type II diabetic women it was found that three grams of fish oil per day (containing 1.8 grams of omega 3 fatty acids like DHA) given for two months reduced total fat mass as well as reduced the size of fat cells.  Inflammatory genes operating within fat were also reduced, an important result indicating that leptin status was improved (though not directly measured).  This study shows how fish oil can improve unhealthy body composition even in individuals with significantly disturbed metabolism.

Also important in these findings is that the fish oil also improved circulatory health, a key concern of any person with diabetes. 

Fish oil, and DHA in particular, have gone to the front of the line as a health promoting substance for brain function, cardiovascular function, and weight management.  Because omega 3 oils are woefully lacking in the processed diets eating by most Americans and because fish is often contaminated with mercury, molecularly distilled fish oil modified for high content of DHA is clearly the top fish oil supplement on the market today.

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Supplements that contain DHA

Other Weight Loss News:


Losing weight is hard enough, keeping it off is even harder.  New research shows that even after maintaining an amount of weight loss for greater than one year, basal metabolism may still be in “hibernation” mode.


An emerging body of scientific data suggests that a lack of friendly flora in your digestive tract helps you store fat and become overweight.  Researchers tested this in pregnant women, measuring the gut flora over the course of their pregnancy (in both overweight women and normal weight women).


Several new studies into colon cancer have identified early changes that turn on wrong gene switches that in turn cause colon cancer.  One study links obesity to colon cancer, the other study links digestive inflammation to colon cancer.  The good news is that by taking proactive steps these adverse changes can be easily stopped.


New research proves for the first time that viral infections activate the synthesis of fatty acids in human metabolism.  In turn these fatty acids are used by the viruses to build the envelope that protects them, a process that is vital for viral replication.  The researchers found that reducing fatty acid synthesis with drugs dramatically reduced viral replication.  I find this study fascinating, but for different reasons.  The information helps to explain why some people have very resistant weight problems, as low grade viral infections would keep a person’s metabolism making fat instead of breaking it down to use for fuel.


New research indicates that problems with endothelial cells may trigger baby fat cells to grow up too fast, regardless of diet, opening up a whole new angle on the weight loss issue.


Until recently nobody knew exactly where your baby fat cells lived.  In a new study clever scientists engineered mice so that baby fat cells would glow green, allowing them to pinpoint their exact location and to follow their development.


A new study points out that the lack of sleep, all by itself, is enough to inappropriately raise cortisol later in the day.  As I explained last week, too much cortisol turns off fat burning gene switches in your liver, leading to obesity risk.


New research has for the first time pinpointed the precise mechanism explaining how excess cortisol results in a fatty liver. 


Mother’s have a profound affect on the future health of their children, including the risk for obesity.  Fetal programming and early infant development are times when the nervous system is “hard wiring” patterns that will have heavy influence for a lifetime.


Research published in the September 1 issues of the Journal Sleep shows that if you snore more than half the night you have a 64% chance of having measurable hardening of your carotid artery – a major cause of stroke.


This week the New England Journal of Medicine published a groundbreaking study linking low levels of BDNF (Brain Derived Neurotrophic Factor) to obesity.


After a detailed molecular analysis of the fat of obese individuals compared to the fat of lean individuals it was discovered that the obese fat contained so many abnormalities relating to poor metabolic function that the researchers described it as “sick fat.”


The government-sponsored food pyramid has been linked to the obesity epidemic for some time.  I have said for many years that if you want to look like a pyramid then eat like one.  The refined and excess carbohydrate plan that is the food pyramid has just been dealt a death blow


Researchers at the American Psychological Association’s annual meeting presented multiple studies linking the frequency of childhood ear infections to the risk of obesity.


Individuals are deluded to think that drinking beverages containing no-calorie sweeteners will help them lose weight or at least not gain weight.  A new study continues to debunk this myth. 


The near-useless FDA has said for a long time that the ingestion of MSG was safe, and so it is used as an addictive flavor additive in countless processed and branded foods in the United States.  A new study of Chinese citizens says otherwise, showing that ingestion of MSG is directly linked to obesity.


Early impairment of nerve-related function is a clear risk for developing later-life obesity, so concludes new research published in the British Journal of Medicine. 


New imaging technology is enabling researchers to understand the relationship of thyroid function and just how well your brain works. 


A new study shows that men and women who eat two eggs for breakfast lose 65% more weight than those who have a bagel breakfast of equal calories. 


Low levels of dopamine in your brain will cause you to eat more food so that you feel good.  New research shows that obese animals have half the dopamine levels of normal, and it took much more stimulation to get an adequate release of pleasure. 


There is a right way to lose weight and a wrong way.  The wrong way is to go on a starvation low-calorie diet and induce the leptin starvation response.  When this happens you lose bone mass and weight, and you are much more likely to gain the weight back later.  New research shows that the jolt to your bones may continue even after the weight loss has stopped.


Several rather sobering studies were published this week regarding the costs of obesity and its current trend. 


As your body fat goes up inflammation increases in your body, in turn generating excessive free radical damage.  That is the conclusion of a new study measuring these relationships in women age 35-50.  Undoubtedly, this data holds true for any overweight person of any age.


A novel animal study has shown that nutrition can influence the ways genes are expressed during pregnancy, so that the newborn is less likely to become obese.  This study has far reaching implications for public health because right now many overweight mothers are predisposing their children to be overweight through improper gene programming.


A new study closely tracks the relationship of appetite to the development of obesity in children, hoping to shed light on why some kids don’t get fat and others do.  The researchers found that as a child’s waistline gets larger, the full signal is blunted or delayed and the desire for food intake increases.


A new study shows that carnosine promotes the normal function of nerves to stimulate the breakdown of fat via histamine receptors.


New concepts in the management of diabetes are taking center stage in our society because widespread dietary and lifestyle abuse has led to an epidemic of type II diabetes in children, teenagers, and young adults.  The use of drugs to manipulate numbers and gene function within cells has thus far proven to be a miserable failure.  Drugs do not restore health, and as a recent clinical trial proves the more aggressively they are used to treat diabetes the higher the risk for death.


A new study in overweight women shows that 900 mg per day of supplemental calcium increases their ability to burn fat for fuel.  This ability is enhanced by vitamin D status.


Too many Americans are addicted to sweet taste and have an adversely altered taste perception.  On the flip side of this coin is a more neutral reaction to bitter-tasting vegetables.  New research in children shows that those with an increased aversion to bitter taste are six times more likely to become obese – a problem that is aggravated if their mother is also overweight.


New research confirms what many of you already know: whatever weight you managed to lose during the week is gained back on the weekend, resulting in Monday morning gloom as you look at the scale.  Saturdays are king of fat intake, topping all other days of the week.


It is convenient for modern medicine to separate a patient’s problems into neatly divided specialty areas so that problems can be micro-analyzed by various specialists.  This is convenient for treating, diagnosing, referring, and drug dispensing.  This system generates income for the sickness industry but it often fails to understand the highly integrated nature of any problem you may be having. 


A new simple way to judge waistline size and health has emerged that applies to children, adults, and either sex.  The goal is to keep your waist size to less than ½ your height.  Just figure out your height in inches and divide by two.


The drug industry is doing everything in its power to get leptin drugs on the market for some type of widespread weight-loss angle.  The problem is that such drugs don’t work, because just about everyone who is overweight makes too much leptin.  This was apparent back in 2002 when there were only 5000 leptin studies, now there are 14,000.  Consumer beware – researchers paid by Big Pharma are actively and intentionally creating a twisted misrepresentation relating to how leptin works, solely to sell drugs.


Embarrassingly, the AMA has voted in defense of high fructose corn syrup, making its entire organization look like a ship of fools.


Researchers documented that a potent brain-derived neurotrophic factor (BDNF) was significantly boosted by 3 months of aerobic exercise – and the higher its level the less a person wants to eat and the greater their weight loss.  This is the first time BDNF levels have been linked to appetite suppression – a significant finding.


In a strange twist of events your stomach’s hunger hormone, ghrelin, may help to protect you against stress-induced anxiety and depression.  This “gift” of protection comes at a price – eating too much food in response to stress.  This new information shows just how powerful stress eating can be, as this type of survival signaling is wired to your core subconscious brain.


Fail to get enough restful sleep and the next day you will crave and eat too many carbohydrates – even getting drawn into the evil of snacking. 


Studies detailing the effects of protein on rat brain neuro-circuitry have shown that higher protein meals increase your subconscious brains satiety signals, helping you feel full. 


A diet of lean protein and low fat dairy, along with vegetables and fruit, was able to stop bone loss during weight loss – something that our government’s food pyramid guidelines could not do.  Study participants consume 30% of their calories from protein, while the food pyramid recommends only 10% of calories from protein.


It’s obvious to just about anyone that excess sugar consumption makes you fat.  Now we even have data to prove that excessive sugar consumption, mostly from sweetened drinks like soda, is up at a rate that would require a 1 hour jog per day just to burn of the extra calories.


Two new studies confirm the helpful role of Pine Nut Oil to reduce the desire to eat larger portions. 


There appears to be a very large disconnect between what a person knows they should be eating and what they tend to eat.  New research is demonstrating that emotional states of feeling, otherwise known as stress eating, take priority over logic when it comes to consuming food.


A new study shows just how deadly refined carbohydrates are – even for a healthy person.  One serving given to a lean and healthy young adult is adequate to triple the inflammatory response to the surge in glucose.


A new study involving Chinese citizens found that MSG intake of 330 mg a day doubled the risk for obesity, independent of diet and exercise.


A new study demonstrates that both estrogen positive and estrogen negative breast cancer in post menopausal women is linked directly to the size of their waistline and consumption of junky carbohydrates.


Research on female monkeys shows that those in a subservient role and under chronic stress ate significantly more food resulting in weight gain, compared to the female monkeys in the dominating role.  New research on humans does show that women with poor stress management skills will keep eating after they are full simply to make negative emotional feelings go away. 


Just about everyone now realizes that the size of your waistline reflects your degree of cardiovascular risk.  A new angle on the issue has emerged and it has to do with your stomach itself, as opposed to the amount of extra belly fat.  It has to do with your stomach’s hunger signal, ghrelin.


  • Digestive Inflammation and Food Cravings,

    Several new lines of research are showing that ghrelin levels are elevated during digestive distress in an effort to coordinate repair of your digestive tract. 
    The adverse side effect of elevated ghrelin is that your appetite will elevate and you will eat more food, making you gain weight.


    A great deal of eating behavior is buried in subconscious brain circuitry that was developed in your early life.  Such programming is more like computer hardware than software, which is why many of us struggle to “change the eating programs.”


    A new study shows that obese individuals have a 40% increased risk for dementia and an 80% increased risk for Alzheimer’s.  Significant mental decline affects 10% of the elderly population and rates of Alzheimer’s are up 20% - consistent with the increase in obesity.  There is no reason this has to happen.


    • Ghrelin Elevated by Sluggish Thyroid Function,

      When you eat less food, especially on a diet, there comes a time when weight loss slows down.  At this time you will start getting an increase in hunger that is coming from a hormone signal in your stomach called ghrelin.  New research shows that ghrelin levels go up (meaning increased hunger) as thyroid function is impaired and becomes sluggish.


      • Big Pharma Eyes Your Stomach,

        Scientists inject ghrelin (pronounced GRAY-lin) into the blood of normal weight people.  While measuring their brain activity these subjects are shown pictures of food and the ghrelin makes them drool.  Core animal pleasure is activated.  Yes, they must have it.  Stimulus-response, a modern Pavlovian dog experiment.


        Extra fat does a lot more than clog arteries.  Inflammatory proteins coming from fat directly damage the heart – whether you feel just fine or not.  That is the conclusion of new John Hopkins Medicine research tracking 7000 obese men and women across the United States – watching them descend from no heart disease into poor cardiovascular health.


        Impaired coordination may be a first sign of sluggish thyroid function.  Are you bumping into things too often?  If so, you may have sluggish thyroid due to faulty leptin function.


        • Low Thyroid Linked to Fatal Heart Disease in Women,

          A stunning thyroid study has just been published in the Archives of Internal Medicine.  It showed that women whose TSH scores were in the high end of the normal range were at a 69% increased risk for cardiovascular death.


          The data is now in and it is not good for the junk food industry.  The more fast food and convenience store outlets in your neighborhood the more likely you are to be obese and diabetic.  The study, Designed for Disease: the Link Between Local Food Environments and Obesity and Diabetes, was conducted in California but certainly applies though out U.S.


          New research now shows that the drop in a fat hormone called adiponectin is associated with an inflammatory-driven decline in kidney function.  By fixing leptin problems adiponectin can be elevated to natural levels and the risk for kidney disease can be lowered.


          Novel mice experiments carried out by researchers at the University of Texas Southwestern Medical Center are helping to clarify the relationship of fat and disease.  Mice bred not to be able to store fat, which were then fed a high fat diet, became diabetic and diseased much faster than the mice who could store the surplus calories as fat.


          It was just discovered that belly fat cells make an appetite signal which increases as you become overweight, causing you to crave more food, which makes you even fatter in the abdominal area, in turn causing you to crave even more food.


          A new British study links inflammation from the womb (low birth weight babies) through early life weight gain and shows that this issue sets the stage for cardiovascular disease in later life.


          The importance of a mom being healthy body weight prior to pregnancy and having good nutritional status and eating habits has now been driven home by a new autism study.  The study showed that children who develop early autism have significantly higher blood levels of leptin.  Those levels are high because of adverse fetal programming due to a leptin resistant mother.


          A wide range of cutting edge obesity research was presented at a Conference held March 28, 2008 in Great Brittan.  The conference focused on the importance of prenatal, postnatal, and early childhood eating as a determinant for later life food choices and obesity risk.


          • Food Addiction and Stress Eating Mechanism Identified,

            By experimenting with mice that were bred to have no sweet-taste ability, a direct link of food intake to pleasure has been identified for the first time.  This mechanism is important because it links food acquisition directly to addictive or stress-related eating “solutions.”


            • A Fat Stomach Sets the Stage for Cognitive Decline,

              A three decade study looked into the relationship between abdominal fat and the risk for developing dementia.  The findings are not good news for any person with extra weight around the middle.  It was revealed that the larger your waistline in your 40s, the greater the risk for developing dementia in later life.


              Scientists are now linking precise mechanisms showing how immune cells stimulate new fat cells, causing obesity.


              • Obesity Increases Risk for Aggressive Breast Cancer,

                A wake up call has been issued to women.  If you are overweight and you get breast cancer it is more likely to be life threatening, and you have significantly poorer odds of being alive 5 or 10 years following treatment if weight issues are not corrected. 


                A fascinating study shows that children lacking good digestive bacteria at birth were much more likely to become overweight by age 7 compared to children with healthy levels of friendly digestive bacteria. 


                New information helps to explain how breast and prostate cancer are linked to obesity.  Two hormones that come from fat, leptin and adiponectin, are involved in the problem.


                • Cancer Risk Goes Up with Body Weight,

                  UK researchers have reviewed 140 studies evaluating body mass index (obesity) and the risk for cancer.  They found that as body weight goes up, cancer risk goes up.  The incidences of various types of cancer were directly linked to progressive obesity.


                  Numerous genes are different in those whose ancestors came from more Northern climates, especially changes in the leptin receptors.  This clearly means the stronger your ancestry is linked to colder climates the more you are genetically predisposed to obesity, high blood pressure, high cholesterol, and heart disease.


                  The latest salvo fired off at the multi-billion dollar sweetener industry found that feeding rats zero-calorie saccharin (the main component of Sweet n’ Low), compared to actually eating sugar, caused them to eat more food in general as well as depressed their metabolic response to food – a double negative that readily promoted weight gain. 


                  Norwegian researchers found that obese individuals were significantly lacking in vitamin B6, vitamin C, vitamin D, and vitamin E.  This lack of nutrients was associated with a mild elevation of C-Reactive protein, an important inflammatory marker.