Special types of citrus-derived flavonoids, known as polymethoxyflavones, especially nobiletin and tangeretin, are inversely associated with cardiovascular disease. Previous studies have shown them to be effective in lowering cholesterol in humans as well as helping to prevent the accumulation of LDL cholesterol in the lining of arteries. Even relatively small amounts of them can activate gene signals that help to correctly metabolize cholesterol. A new study shows that nobiletin can boost adiponectin levels and reduce inflammation within white adipose tissue, thereby significantly improving insulin resistance and lowering high blood sugar. Additionally, a significant body of research has been accumulating in the past few years showing that polymethoxflavones are powerful nutrients in cancer prevention.
Read More: cancer prevention,
cholesterol,
flavonoids,
insulin,
metabolism,
nobiletin,
polymethoxylated flavones,
Tangeretin
Nobiletin and Tangeretin are citrus-derived polymethoxyflavonoids, uniquely structured flavonoids that are now shown to directly interact with white adipose tissue in a way that makes your stored fat much healthier, including the prevention of insulin resistance.
Read More: adiponectin,
insulin resistance,
nobiletin,
Tangeretin,
white adipose tissue
A new study with mice that are programmed to rapidly develop insulin resistance, fatty liver, and atherosclerosis found that nobiletin, a citrus-derived polymethoxylatedflavone, prevented the development of all three problems.
Read More: atherosclerosis,
fatty liver,
high cholesterol,
insulin resistance,
nobiletin,
weight gain
Tangeretin and nobiletin are polymethoxylated citrus flavonoids which have been studied for a number of years for their ability to help lower LDL cholesterol. The latest study demonstrates that their primary activity is to inhibit the production of ApoB by liver cells. ApoB is required for the formation of LDL cholesterol, so if there is less ApoB produced then there has to be less LDL cholesterol.
Read More: ApoB,
cholesterol,
LDL,
nobiletin,
Tangeretin