A new study shows that individuals with anxiety have a disconnect of regulation between the frontal lobes of the conscious brain and a core regulating center in the subconscious brain (amygdala). In normal situations your frontal lobe thought process dampens and regulates the alarm coming from the amygdale, helping to keep negative emotions in check and under control. The new study shows for the first time that this method of self-regulation is lacking in people who have too much anxiety as a baseline of function. In essence, they are lacking anxiety brakes.
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The post-mortem analysis of the brains of patients with schizophrenia compared to normal brain shows severe dysregulation in the matrix outside of brain cells that holds them together in key regions of the subconscious brain associated with learning, memory, and the processing of stress. The finding is the first of its kind and it essentially means that the roads and highways that hold brain cells in position are at least as important as the neurotransmitter status that up to this time has received the lion’s share of attention.
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A child’s relationship with their mother is a key factor in terms of how their brain develops. If the mom is depressed then the child’s brain processes stress differently, leading to a larger amygdala and higher levels of glucocorticoids. This would cause a person to grow up with a brain structure more prone to an aggressive/combative stress response.
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child's stress response,
depressed mom,
excess glucocorticoids