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NF-kappaB Articles:

Grape Seed Extract Lowers White Adipose Tissue Inflammation

One of the most devastating health aspects of being overweight is the change in immune system status within white adipose tissue fat stores. There is a major shift of macrophages into the white adipose tissue which act in a highly inflammatory manner to alter the function of stored fat so that it becomes metabolically incompetent as well as directly adding to the overall inflammatory burden of one’s body. This is why obesity is associated with more prevalence and earlier onset of any of the diseases of aging (cancer, heart disease, Alzheimer’s, etc). A new study shows that grape seed extract can turn down the inflammatory signals and consequent free radical damage from these white adipose tissue macrophages.

Read More:  Cardio Helper, grape seed extract, LeptiCardio Pack™, macrophages, NF-kappaB, Performa Plus™, white adipose tissue

Vitamin K Reduces Inflammation

Vitamin K is known as an important co-factor nutrient in the formation of bone. It enables the attachment of calcium into proper structure as bone hydroxyapatite crystals. Vitamin K is also needed for proper blood coagulation and is well known as an antioxidant, working synergistically with many other antioxidants. A new study shows that vitamin K has the ability to directly modulate NF-kappaB, the primary gene switch involved with inflammation.

Read More:  Daily Bone Xcel™, Daily Energy Multiple Vitamin™, NF-kappaB, Vitamin K

Extra Virgin Olive Oil Reduces Inflammation in Patients with Metabolic Syndrome

Olive oil is a staple of the Mediterranean diet and has long been associated with the reduce risk for heart disease in cultures consuming it. A new study analyzes detailed gene responses in patients with the metabolic syndrome (overweight, high cholesterol, high blood sugar, high blood pressure, low HDL). They demonstrated that extra virgin olive oil significantly reduces the expression of inflammatory genes, whereas refined olive oil has no benefit.

Read More:  Daily Energy Multiple Vitamin™, extra virgin olive oil, metabolic syndrome, NF-kappaB, phenol, Squalene

Blueberry Extract Inhibits Breast Cancer Cells

Blueberries are one of the best studied nutrients for mind and metabolic health. Now comes a new study showing they can inhibit a variety of cancer cells – more good news for blueberries.

Read More:  Blueberries, NF-kappaB, PoliBlue™

Chondroitin Sulfate Lowers Core Inflammatory Signal

Chondroitin sulfate and glucosamine are popular joint support nutrients with over a decade of documentation showing their assistance for both osteoarthritis and rheumatoid arthritis. These nutrients have generally been considered as building blocks for physical structure, like 2 x 4s and plywood for a house. However, a number of new studies now show that chondroitin sulfate actually regulates the core inflammatory gene signal known as NF-kappaB. This finding significantly expands on the importance of chondroitin sulfate as a health promoting nutrient.

Read More:  chondroitin, Chondroitin Plus, Chondroitin Sulfate, joints, NF-kappaB

Vitamin C Deficiency Increases Risk for Bone Loss

The lack of vitamin C within bone macrophages can lead to the excessive formation of osteoclasts that cause bone loss. Just as every individual needs savings for financial security so it is that your body needs a savings of antioxidants for health security.

Read More:  antioxidants, bone loss, NF-kappaB, Vitamin C

Human Study Proves Resveratrol Lowers Inflammatory Gene Signaling

A common dietary supplement form of resveratrol, taken at the relatively low dose of 40 mg per day for 6 weeks, could turn down the primary inflammatory gene signal known as NF-kappaB and consequently lower key markers of inflammation such as TNFa, IL6, and C-reactive protein. Since the inflammatory problem is underlying the deteriorating health of just about anyone, including the process of accelerated aging, this human study data is very significant.

Read More:  CRP, IL6, inflammation, NF-kappaB, Resveratrol, TNFa

Can Blueberries Protect Against Alzheimer’s and Parkinson’s?

Professor Douglas Kell of the University of Manchester has published an extensive article explaining how uncontrolled iron is a common theme in many degenerative diseases such as Alzheimer's and Parkinson's wherein the inflammatory gene signal NF-kappaB is inappropriately activated and excessive cell death results. Blueberries--along with other antioxidants--may be the answer, as the blueberries have been found to be a potent natural iron chelator.

Read More:  Alzheimer's, Blueberries, free radical damage, NF-kappaB, Parkinson's

Bromelain Has Potent Anti-Cancer Properties

Nutrients such as bromelain and papain contain protease enzymes that have long been used for their anti-inflammatory properties, enhancement of tissue healing, and as part of anti-cancer nutrient support. The research supporting the use of bromelain as a tool in the war on cancer has been building over the past several years. Researchers have now identified several cancer-killing mechanisms of bromelain, including deactivation of the key gene signal NF-kappaB and induction of the autophagy process that causes the cancer cell to self destruct.

Read More:  autophagy, bromelain, cancer, enzyme, inflammation, NF-kappaB, papain

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