Undecylenic Acid Inhibits Candida Biofilm Formation

Byron's Comments:

Reducing changes in Candida that lead to biofilm formation is vital to keeping Candida in healthy balance.

Study Title:

Undecylenic acid inhibits morphogenesis of Candida albicans.

Study Abstract:

Resilient liners are frequently used to treat denture stomatitis, a condition often associated with Candida albicans infections. Of 10 liners tested, 2 were found to inhibit the switch from the yeast form to hyphae and a third was found to stimulate this switch. The inhibitor was determined to be undecylenic acid.

Study Information:

McLain N, Ascanio R, Baker C, Strohaver RA, Dolan JW. Undecylenic acid inhibits morphogenesis of Candida albicans. Antimicrob Agents Chemother.   2000 October  44(10):2873-5.
Molecular and Cellular Biology & Pathobiology Program, Medical University of South Carolina, Charleston, South Carolina 29425, USA.

Full Study:

http://aac.asm.org/cgi/content/full/44/10/2873?view=long&pmid=10991877


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