Quercetin, Chondroitin, and Glucosamine Help Osteoarthritis

Byron's Comments:

Quercetin is a potent 5 lipoxygenase inhibiting nutrient. Here, its anti-inflammatory properties are combined with the cartilage and synovial fluid boosting properties of glucosamine and chondroitin to show improvement in patients with osteoarthritis.

Study Title:

Effects of an Oral Administration of Glucosamine-Chondroitin-Quercetin Glucoside on the Synovial Fluid Properties in Patients with Osteoarthritis and Rheumatoid Arthritis.

Study Abstract:

The effects of an orally administered combination of a glucosamine-chondroitin-quercetin glucoside (GCQG) supplement on the synovial fluid properties of patients with osteoarthritis (OA) and rheumatoid arthritis (RA) were investigated from the clinical nutrition view point. In this study, forty-six OA and twenty-two RA patients were administered with the GCQG supplement orally for 3 months. Several parameters of the knee joints were monitored before and after supplementation. The OA patients showed a significant improvement in pain symptoms, daily activities (walking and climbing up and down stairs), and visual analogue scale, and changes in the synovial fluid properties with respect to the protein concentration, molecular size of hyaluronic acid, and chondroitin 6-sulphate concentration were also observed. However, no such effects were observed in the RA patients. These results suggest that the GCQG supplement exerted a special effect on improving the synovial fluid properties in OA patients.

Study Information:

Matsuno H, Nakamura H, Katayama K, Hayashi S, Kano S, Yudoh K, Kiso Y. Effects of an Oral Administration of Glucosamine-Chondroitin-Quercetin Glucoside on the Synovial Fluid Properties in Patients with Osteoarthritis and Rheumatoid Arthritis. Biosci Biotechnol Biochem. 2009 February Vol. 73, No. 2 pp.288-292.
Matsuno Clinic for Rheumatic Diseases.

Full Study:

http://www.jstage.jst.go.jp/article/bbb/73/2/73_288/_article

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