Friendly Flora Inhibits Toxin Release by E. Coli

Byron's Comments:

Another angle on the beneficial help of friendly flora to combat infectious E. coli.

Study Title:

Probiotic inhibits the cytopathic effect induced by Escherichia coli O157:H7 in Vero cell line model.

Study Abstract:

AIMS: The effectiveness of four strains of Bifidobacteria against enterohemorrhagic Escherichia coli O157:H7 infection was studied using a Vero cell model.

METHODS AND RESULTS: E. coli O157 was inoculated on the Vero cell line before and after treatment with probiotic. The cytopathic effect (CPE) was evaluated during 24 h of incubation. The results indicated that Shiga toxin activity was inhibited by the probiotic. To prevent a Stx2 CPE, the probiotic needs one log more than the Stx1.

CONCLUSION: The Vero cell assay, in particular, is a good model to evaluate the effect of Bifidobacteria inhibiting bacterial attachment because of soluble substances and the competitive aspect and could be used in a variety of foods like milk and yoghurt to protect pathogen bacteria.

SIGNIFICANCE AND IMPACT OF THE STUDY: Probiotics could control pathogenic bacteria and Vero cell introduce as a model for evaluation of probiotics against pathogen bacteria.

Study Information:

Tahamtan Y, Kargar M, Namdar N, Rahimian A, Hayati M, Namavari MM. Probiotic inhibits the cytopathic effect induced by Escherichia coli O157:H7 in Vero cell line model. Lett Appl Microbiol.   2011 May  52(5):527-31.
Razi Vaccine and Serum Research Institute, Shiraz, Iran  Department of Microbiology, Islamic Azad University, Jahrom Branch, Jahrom, Iran.

My cart is empty.   View Cart |  Login

• How Protein Helps Weight Loss
  
• The Five Rules of The Leptin Diet
  
• The Facts on Magnesium Stearate
  
• Body Temperature and Thyroid Problems
  
• Unclog Your Liver & Lose Abdominal Fat – Leptin Diet Weight Loss Challenge #6
  



Connect with Wellness Resources: