Tocotrienols in cardioprotection.

Byron's Comments:

Tocotrineols may well be the single best cardiovascular protective nutrient. Read more.

Study Title:

Tocotrienols in cardioprotection.

Study Abstract:

Tocotrienols, a group of Vitamin E stereoisomers, offer many health benefits including their ability to lower cholesterol levels, and provide anticancer and tumor-suppressive activities. Several recent studies determined the cardioprotective abilities of tocotrienols, although the number is only 1% compared to the study with tocopherols. Both in acute perfusion experiments and in chronic models, tocotrienols attenuate myocardial ischemia-reperfusion injury, artherosclerosis, and reduced ventricular arrythmias. Apart from the antioxidative role of tocotrienols, it appears that tocotrienols mediated cardioprotection is also achieved through the preconditioning-like effect, the best yet devised method of cardioprotection. Hence, tocotrienols likely fulfills the definition of a pharmacological preconditioning agent and give a tremendous opportunity to place tocotrienols as an important therapeutic option in cardiovascular system.

Study Information:

Das S, Nesaretnam K, Das DK. Tocotrienols in cardioprotection. Vitam Horm.  2007 March  76:419-33.
Cardiovascular Research Center, University of Connecticut School of Medicine, Farmington, Connecticut 06030, USA.

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