Telomeres, Aging, and Nutrients

Byron's Comments:

This study offers proof of extended longevity from taking a multivitamin.

Study Title:

Multivitamin use and telomere length in women

Study Abstract:

Background: Telomere length may be a marker of biological aging. Multivitamin supplements represent a major source of micronutrients, which may affect telomere length by modulating oxidative stress and chronic inflammation.

Objective: The objective was to examine whether multivitamin use is associated with longer telomeres in women.

Design: We performed a cross-sectional analysis of data from 586 early participants (age 35–74 y) in the Sister Study. Multivitamin use and nutrient intakes were assessed with a 146-item food-frequency questionnaire, and relative telomere length of leukocyte DNA was measured by quantitative polymerase chain reaction.

Results: After age and other potential confounders were adjusted for, multivitamin use was associated with longer telomeres. Compared with nonusers, the relative telomere length of leukocyte DNA was on average 5.1% longer among daily multivitamin users (P for trend = 0.002). In the analysis of micronutrients, higher intakes of vitamins C and E from foods were each associated with longer telomeres, even after adjustment for multivitamin use. Furthermore, intakes of both nutrients were associated with telomere length among women who did not take multivitamins.

Conclusion: This study provides the first epidemiologic evidence that multivitamin use is associated with longer telomere length among women.

Study Information:

Qun Xu, Christine G Parks, Lisa A DeRoo, Richard M Cawthon, Dale P Sandler and Honglei Chen. Multivitamin use and telomere length in women Am J Clin Nutr  2009 June  89: 1857-1863, 2009.
Epidemiology Branch, National Institute for Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC.




Related Entries: Nutrition Makes Anti-Aging Possible: Secrets of Your Telomeres
Hayflick Comments on Aging


Most Popular News:


Connect with Wellness Resources:

Connect on Facebook Follow us on Twitter Wellness Resources on Pinterest Wellness Resources YouTube Channel Get RSS News Feeds
Telecourse
bookstore
Thyroid and Metabolism
podcast
autoship