Noni Reduces Liver Lesions Upon Toxic Exposure

Byron's Comments:

A nutrient that is both immune supportive and liver protective has properties that are supportive of better health.

Study Title:

Liver protective effects of Morinda citrifolia (Noni).

Study Abstract:

This study evaluated the protective effects of Noni fruit juice on acute liver injury induced by carbon tetrachloride (CCl(4)) in female Sprague-Dawley (SD) rats. Liver damage (micro-centrilobular necrosis) was observed in animals pretreated with 20% placebo (drinking water) + CCl(4). However, pretreatment with 20% Noni juice in drinking water + CCl(4) resulted in markedly decreased hepatotoxic lesions. Furthermore, serum alanine aminotransferase and aspartate aminotransferase levels were significantly lower in the Noni group than the placebo group. In a correlative time-dependent study, one dose of CCl(4) (0.25 mL/kg in corn oil, p.o.) in female SD rats, pretreated with 10% placebo for 12 days, caused sequential progressive hepatotoxic lesions over a 24 h period, while a protective effect from 10% Noni juice pretreatment was observed. These results suggest that Noni juice is effective in protecting the liver from extrinsic toxin exposure.

Study Information:

Wang MY, Nowicki D, Anderson G, Jensen J, West B. Liver protective effects of Morinda citrifolia (Noni). Plant Foods Hum Nutr.  2008 June  63(2):59-63.
Department of Pathology, University of Illinois College of Medicine, Rockford, IL 61107, USA.

Full Study:

http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=18317933

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