Fiber Reduces Breast Cancer Recurrence

Byron's Comments:

Fiber helps clear estogen and promote a favorable metabolic hormone profile for health, rather than a low-fiber profile that increases female cancer risk.

Study Title:

Dietary fiber is associated with serum sex hormones and insulin-related peptides in postmenopausal breast cancer survivors.

Study Abstract:

OBJECTIVE: To measure the association between dietary fiber intake and eleven hormones and peptides in postmenopausal breast cancer survivors.

METHODS: Intake of fiber from food and supplements was measured two to three years after breast cancer diagnosis in 493 postmenopausal women from three western states. Concurrently, a fasting blood sample was obtained for assay of estrone, estradiol, free estradiol, testosterone, free testosterone, dehydroepiandrosterone sulfate, sex hormone-binding globulin (SHBG), leptin, C-peptide, insulin-like growth factor-1 (IGF1), and IGF-binding protein-3. Adjusted means of these hormones and peptides were calculated for categories of fiber intake.

RESULTS: High intake of dietary fiber was significantly (P

CONCLUSION: High fiber diets may be beneficial to postmenopausal breast cancer survivors due to fiber’s favorable influence on sex hormones and peptides known to affect breast cancer prognosis.

Study Information:

Wayne SJ, Neuhouser ML, Ulrich CM, Koprowski C, Baumgartner KB, Baumgartner RN, McTiernan A, Bernstein L, Ballard-Barbash R. Dietary fiber is associated with serum sex hormones and insulin-related peptides in postmenopausal breast cancer survivors. Breast Cancer Res Treat.  2008 November  112(1):149-58.
New Mexico Tumor Registry, MSC 11 620, 1 University of New Mexico, Albuquerque, NM 87131-0001, USA.

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