Byron's Comments:

The studies in the previous section all explain how the nutrients in Stress Helper improve stress tolerance, thereby lowering the negative effect of stress on thyroid function. This study shows that ALC helps promote normal liver metabolism of calories, by helping the liver compensate for sluggish thyroid function.

Study Title:

Acetyl-L-carnitine increases cytochrome oxidase subunit I mRNA content in hypothyroid rat liver.

Study Abstract:

The effect of acetyl-L-carnitine on the quantity of the messenger RNA for the subunit I of cytochrome oxidase in the liver mitochondria of hypothyroid rat was measured by Northern blot and solution hybridization. Three hours after pre-treatment of hypothyroid rat with acetyl-L-carnitine, the level of the transcript increased strongly. This effect was also obtained when acetyl-L-carnitine was administered to T3 pre-treated hypothyroid rats. These results add further evidence to the suggestion that acetyl-L-carnitine is able to stimulate mitochondrial transcription under altered metabolic conditions.

Study Information:

Gadaleta MN, Petruzzella V, Fracasso F, Fernandez-Silva P, Cantatore P.  Acetyl-L-carnitine increases cytochrome oxidase subunit I mRNA content in hypothyroid rat liver.  FEBS Lett.   1990 December  277(1-2): 191-3.
Dipartimento di Biochimica e Biologia Molecolare, Universita di Bari, Italy.

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