R-Alpha Lipoic Acid and Acetyl-L-Carnitine Protect Against Parkinson’s

Sunday, May 02, 2010  -  Byron Richards, CCN
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Nerve cells have very high energy requirements to sustain healthy function.  As a component in any problem of neurological malfunction and deterioration that is a corresponding decline in nerve cell energy production.  A new study shows that a combination of R-Alpha Lipoic Acid and Acetyl-L-Carnitine1 were synergistically able to maintain nerve cell energy production, even in the face of experimentally induced Parkinson’s.

When scientist want to study Parkinson’s in animals they create an animal model of Parkinson’s by poisoning the animal with rotenone, a toxic pesticide that is highly attracted to the energy-producing mitochondria Organelle found in cells that produce ATP or chemical energy. Also involved with cell signaling, cellular differentiation, cell death, cell growth, along with heme and steroid synthesis. of nerve cells.  In this study animals were pre-treated for four weeks with ALA and ALC before exposure to rotenone.

The researchers found that pretreatment with these powerful antioxidant nutrients increased the ability of mitochondria Organelle found in cells that produce ATP or chemical energy. Also involved with cell signaling, cellular differentiation, cell death, cell growth, along with heme and steroid synthesis. to self-regenerate as well as significantly lower the production of free radicals within nerve cells.  The researchers concluded that this combination of nutrients “might be an effective and safe prevention strategy for Parkinson’s Disease.”  I would add that the anti-aging mechanism of these nutrients is likely to apply to nerve health in general and is one excellent protective strategy for nerves in general.

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Referenced Studies:
  1. ^ R-Alpha Lipoic Acid and Acetyl-L-Carnitine Offset Rotenone Induced Damage  J Cell Mol Med  Zhang H, Jia H, Liu J, Ao N, Yan B, Shen W, Wang X, Li X, Luo C, Liu J.

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