Quercetin Lowers Respiratory Inflammation, Activates SIRT1

Sunday, January 30, 2011
Byron J. Richards, Board Certified Clinical Nutritionist
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In a recent study, mice were given toxins to produce lung damage that mimicked chronic obstructive pulmonary disease (COPD) and emphysema. Quercetin1 treatment for 10 days significantly improved the lungs, reducing free radical damage and inflammation. It also upregulated the longevity gene SIRT1 Considered the "longevity protein" known for its life spanning effects. It has been shown to inhibit cancer and promote longevity.—this is the first time quercetin has been shown to activate this gene.

While many current and former smokers wind up with COPD, many others are suffering from excess pollution and various common chemical exposures. When the lungs become a weak spot, they are more susceptible to infections that can linger. It is also more difficult to get oxygen into your body, handicapping health at a fundamental level.

When the researchers blocked SIRT1 Considered the "longevity protein" known for its life spanning effects. It has been shown to inhibit cancer and promote longevity. activation, quercetin was no longer able to protect the lungs. This is a novel finding and indicates an additional potent mechanism by which quercetin may help extend the survival of stressed cells in your sinuses and lungs.

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Referenced Studies:
  1. ^ Quercetin, SIRT1 Activation, Respiratory Protection  Respir Res.  Ganesan S, Faris AN, Comstock AT, Chattoraj SS, Chattoraj A, Burgess JR, Curtis JL, Martinez FJ, Zick S, Hershenson MB, Sajjan US.

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