Pomegranate Extract is a Potent Candida Killer

Thursday, July 25, 2013
By: Byron J. Richards,
Board Certified Clinical Nutritionist
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Pomegranate extracts standardized for their primary active component, punicalagin, have received considerable attention for their role cardiovascular protection, weight management, and cancer prevention. Punicalagins are the most important active component found in the fresh pomegranate fruit; these are typically lost or in very low amounts when pomegrante juice is made. A new study shows that punicalagins have potent anti-fungal activity1 against Candida albicans.

A detailed electron microscopic examination of yeast cells exposed to punicalagins showed that their cell membranes had been drastically disrupted.  This is incredibly important, since Candida survives by erecting a powerful “force field” around its cell membranes. The researchers also combined punicalagins with the anti-fungal drug Diflucan (fluconazole) and found that Diflucan was now twice as effective. Candida drug resistance to Diflucan is a major concern worldwide and the use of Diflucan has adverse side effects to a person’s adrenal glands as the drug is not specific for yeast cells and can disturb normal steroid stability of adrenal hormones. 

Many Americans live with chronic Candida albicans problems as a result of a history of overuse of antibiotics, steroidal medications, alcohol, and/or high sugar diets. While these problems ebb and flow in intensity, many people struggle with the poor digestive health and sinus issues that often results. Candida albicans overgrowth is a primary cause of asthma, which is now an epidemic in antibiotic over-exposed children. The toxins of Candida cause mental decline (brain fog, memory loss, and depression) while increasing the risk for heart disease, cancer, and obesity. In other words, the Candida issue is highly relevant to many Americans. 

It is nice to have one more documented nutrient option in the battle against excessive Candida albicans.


Referenced Studies:
  1. ^ Punicalagins Combat Candida Albicans  Res Microbiol  Endo EH, Garcia Cortez DA, Ueda-Nakamura T, Nakamura CV, Dias Filho BP.

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