How Curcumin & Resveratrol Protect Joints While Helping Your Mood

Wednesday, May 22, 2013
By: Byron J. Richards,
Board Certified Clinical Nutritionist
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When confronted with a higher-than-baseline amount of stress, your body initiates an inflammatory reaction, fundamentally to take quick action and survive. This is highly useful if you have to run away from or fight a saber tooth tiger, but it may not be such a good thing if you are experiencing stress while sitting at your desk or on a couch. This is especially true if stressors, whether real or imaginary, are ongoing in nature. Science shows how a synergistic combination of resveratrol Natural phenol or type of antioxidant found in red grapes, red wine. Research has shown beneficial effects as anti-cancer and anti-inflammatory agents along with supporting healthy blood sugar and cardiovasculature function. and curcumin deactivate stress signals that cause joint destruction and poor mood. It is simply amazing how helpful many nutrients are in terms of allowing us to cope with the day-to-day demands that may otherwise induce wear and tear and accelerate the aging process.

Gene science is just beginning to understand which genes and their related signals become overactive in response to chronic stress. And scientists are now beginning to connect the dots in terms of the health consequences. For example, excessive MAPK and its byproducts can destroy joint cartilage. One study shows that a synergistic combination of resveratrol Natural phenol or type of antioxidant found in red grapes, red wine. Research has shown beneficial effects as anti-cancer and anti-inflammatory agents along with supporting healthy blood sugar and cardiovasculature function. and curcumin can turn down the volume knob on stress-related MAPK signaling, thus enabling your cartilage-building carpenter cells, known as chondrocytes, to survive. Since deteriorating joint health is a major concern for an aging American population, such a finding is of immense benefit.

Interestingly, another study shows that excessive MAPK activation reduces brain levels of serotonin, inciting the type of nervous system “brain pain” that results in depression, anxiety, drug cravings, and addiction. This study shows a precise pathway whereby an excess amount of stress triggers a cascade of events that induce serious nerve problems — all resulting from excessive MAPK signaling.

While resveratrol Natural phenol or type of antioxidant found in red grapes, red wine. Research has shown beneficial effects as anti-cancer and anti-inflammatory agents along with supporting healthy blood sugar and cardiovasculature function. and curcumin are not part of this second study, it is logical to conclude that their reduction of MAPK signaling (regarding joints) would apply anywhere in your body, since both nutrients are known to reduce inflammation in nerves and elsewhere. 

Collectively, the data indicate that synergistic combinations of anti-inflammatory nutrients, such as resveratrol Natural phenol or type of antioxidant found in red grapes, red wine. Research has shown beneficial effects as anti-cancer and anti-inflammatory agents along with supporting healthy blood sugar and cardiovasculature function. and curcumin, are likely to improve your body’s ability to cope with the demands of stress. Since very few of us are likely to have stress-free lives, it is important that we have multiple strategies to offset such wear and tear. Lifestyle factors such as eating well, exercising, getting enough sleep, properly managing stress, and receiving high-quality nutrition should all be part of your anti-inflammatory team.

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