L-Theanine Helps Memory, Prevents Beta Amyloid Induced Nerve Cell Death

Tuesday, January 12, 2010  -  Byron Richards, CCN
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L-theanine’s original claim to fame is as a relaxing nutrient.  Taken before bed it can help you sleep.  Taken during the day it can help you relax and focus.  A new study significantly expands on the nerve benefits of L-theanine, showing that it can prevent the accumulation and biological adverse effects of peptide amyloid beta, the compound associated with progressive mental decline and Alzheimer’s disease.

In this animal study the researchers showed that L-theanine blunted the adverse effects of amyloid beta (which are memory impairment and nerve cell death).  It actually had the ability to reduce levels of amyloid beta, which is how our brains work when they are healthy.  L-theanine directly boosted cellular glutathione in brain cells preventing damage to fats that make up brain cells.  And last but not least, L-theanine regulated the key inflammatory gene signal, NF-kappaB Protein complex that controls DNA transcription and is involved with cellular responses to stress, cytokines, free radicals, UV radiation, oxidized LDL, and infections. , which is vital to healthy brain function.

The researchers concluded that “L-theanine may be useful in the prevention and treatment of Alzheimer’s Disease.”

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