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Health & Wellness News From Byron J. Richards
How Grape Seed Extracts Stop Alzheimer’s PlaqueWednesday, November 26, 2008 - Byron Richards, CCNEarlier this year researchers published data showing that grape seed extract polyphenols could prevent Alzheimer’s plaque from forming in mice. In their latest experiments they sought to determine exactly how grape seed extract was able to work its magic. Using advanced technology (CD spectroscopy, photo-induced cross-linking of unmodified proteins, thioflavin T fluorescence, size exclusion chromatography, and electron microscopy) the researchers identified how grape seed extracts prevented the formation of disease-related amyloid β-protein (Aβ40 and Aβ42). The researchers found that it was rather simple. The grape seed extracts simply prevented amyloid proteins from folding into shapes that form plaque. If they can’t fold they can’t form. While these are animal studies and human trials will now get under way, the research is significant to tens of millions of Americans. The authors summarized their findings “If the Aß proteins can’t assemble, toxic aggregates can’t form, and thus there is no toxicity. Our work in the laboratory, and Mt. Sinai’s Dr. Giulio Pasinetti’s work in mice, suggest that administration of the compound to Alzheimer’s patients might block the development of these toxic aggregates, prevent disease development and also ameliorate existing disease.” Related Entries: Grape Seed Extract’s Powerful Cardio Protection Helping Glial Cells will Revolutionize Prevention & Treatment of Alzheimer’s Scientists Use Grape Seed Extract in the War on Cancer Consistent Intake of Grape Seed Extract is Best for Your Brain High Cholesterol in Middle Age Linked to Future Alzheimer’s Risk Grapes Prevent Heart Damage BDNF Prevents and Reverses Alzheimer’s Disease Grape Seed Extract Stops Leukemia Cells Friendly Nitric Oxide is Needed for Nerve Health ### Supplements that contain grape seed extract Other Health News
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