Higher Dose DHA and EPA Reduce Infection Toxins

By: Byron J. Richards, Board Certified Clinical Nutritionist

Cardiovascular researchers have demonstrated in healthy volunteers that a higher dose of EPA and DHA is effective at reducing the inflammation associated with bacterial toxins, a finding that is highly relevant to the severity of bacterial infection as well as cardiovascular health.

The researchers tested two doses of EPA and DHA, a lower does of 900 mg (EPA 465, DHA 375) or four times that dose. Then injected bacterial endotoxin (lipopolysaccharides or LPS) into the volunteers. All of those on the higher dose, but not the lower dose, had significant reductions in inflammatory markers and fever.

The severity of bacterial infection is marked by the amount of LPS generated during bacterial replication. Your body will heat up (fever) in an effort to dissolve LPS, a natural defense system against toxins. This study shows that higher intake of these oils during infection would help clear these toxins faster.

Many people with poor cardiovascular health have bacterial infections as a significant component of the problem. This can be due to chronic low grade dental, sinus, or digestive infections. In such situations, especially periodontal problems, LPS is entering the blood stream and inducing inflammatory changes that cause plaque formation in the arteries. In many cases this is a primary source of cardiovascular stress, and in other situations, it is simply a percentage of the problem. Higher intake of DHA and EPA is helpful in reducing the metabolic stress of this relatively common toxic issue.

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