Grape Seed Extract Improves Collagen Flexibility & Strength

Tuesday, May 28, 2013
By: Byron J. Richards,
Board Certified Clinical Nutritionist
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Grape seed extract (GSE) is one of nature’s most versatile nutrients, acting as a collagen, artery, and heart strengthener, while providing potent antioxidant and anti-inflammatory activity. I have previously reviewed these attributes in my feature-length article, Grape Seed Extract’s Powerful Cardio Protection. A number of recent studies show GSE to increase collagen strength within teeth—something the dental industry is considering using for better adhesion of composite resin to the dentin of teeth2.

These studies indicate the power of grape seed extract to reinforce the tensile strength of collagen. Think of a strand of collagen like a triple-stranded ski tow rope. The strands are held together with linking structures that are dependent on vitamin C and the amino acid lysine. Under stress and wear and tear, these collagen strands can unravel, leading to a loss of collagen elasticity and functional integrity (meaning aging). GSE has a unique ability to directly act as a collagen-bonding nutrient, thereby improving the strength and flexibility of collagen. 

Earlier researchers have pointed out that this unique ability of GSE to improve collagen enhances skin health and elasticity, provides UV protection, and lowers risk for skin cancer4. The same collagen-enhancing principles apply to collagen virtually everywhere in the body, helping to improve flexibility of joints and elasticity of arteries.

More recent studies show the ability of GSE to protect against nerve damage from high blood sugar5 and joint destruction from rheumatoid arthritis6. Whether your structural problems are large or small, or you just want to keep your collagen as youthful as possible, grape seed extract is a top choice nutrient for your anti-wear-and-tear team.


Referenced Studies:
  1. ^ Grape Seed Extract Improves Dentin Collagen Stability  J Dent Res.  Macedo GV, Yamauchi M, Bedran-Russo AK.
  2. ^ Grape Seed Extract Enhances Dentin Bond Strength  J Biomed Mater Res B Appl Biomater.  Al-Ammar A, Drummond JL, Bedran-Russo AK.
  3. ^ The Collagen Strengthening Properties of Grape Seed Extract  J Med Food.  Shi J, Yu J, Pohorly JE, Kakuda Y.
  4. ^ Grape Seed Extract Helps Protect Against Skin Cancer  Mol Nutr Food Res.  Katiyar SK.
  5. ^ Grape Seed Extract Helps Prevent Diabetic Neuropathy   J Nutr Sci Vitaminol (Tokyo).  Cui XP, Li BY, Gao HQ, Wei N, Wang WL, Lu M.
  6. ^ Grape Seed Extract Reduces the Effects of Induced Arthritis  Immunol Lett  Cho ML, Heo YJ, Park MK, Oh HJ, Park JS, Woo YJ, Ju JH, Park SH, Kim HY, Min JK.

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