Grape Extract Reduces Fat Cell Inflammation

Friday, April 30, 2010  -  Byron Richards, CCN
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The health of your white adipose tissue is central to your well being.  Virtually any condition of poor metabolic function has unfit fat as a primary component of the problem.  For example, as inflammation rises insulin resistance sets in.  A new study shows that grape extract1 can reduce the inflammatory signals coming from human fat cells and resolve insulin resistance, making this a valuable nutrient as part of your weight management efforts.

Dysregulation of your white adipose tissue is marked by an increase in inflammation coming from this tissue, sort of like a swollen ankle but in this case swollen fat.  The key immune system signals involved are TNFa Cytokine involved with systemic inflammation and regulation of immune cells. It is able to induce cell death, and inhibits tumorigenesis and viral replication. When dysfunctional it is associated with a number of disease processes. and IL6, and at the gene level NF-kappaB Protein complex that controls DNA transcription and is involved with cellular responses to stress, cytokines, free radicals, UV radiation, oxidized LDL, and infections. .  The researchers found that grape extract could directly attenuate the production of TNFa Cytokine involved with systemic inflammation and regulation of immune cells. It is able to induce cell death, and inhibits tumorigenesis and viral replication. When dysfunctional it is associated with a number of disease processes. by fat cells, thereby reducing IL6 and NF-kappaB Protein complex that controls DNA transcription and is involved with cellular responses to stress, cytokines, free radicals, UV radiation, oxidized LDL, and infections. .  It further supported the integrity of gene cell signaling that promoted better function of insulin and uptake of sugar into cells, thereby having a favorable influence on helping to combat insulin resistance.

Nutrients are tools to help you improve your health.  Grape extract is a nice tool to have in your toolbox for many reasons.

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Referenced Studies:
  1. ^ Grape Extract and Fat Cell Inflammation  The Journal of Nutritional Biochemistry  Chia-Chi Chuanga, Akkarach Bumrungpertb, Arion Kennedya, Angel Overmana, Tiffany Westa.

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