Cissus Quadrangularis – A Potent Bone Builder

The herb Cissus quadrangularis¹ is widely used in traditional Ayurvedic medicine for its profound bone healing and bone mending properties.  New scientific exploration is helping to document the power of this unique bone support nutrient.  The latest study whows that it directly helps bone marrow make the bone-building carpenter cells known as osteoblasts as well as directly promoting the formation of calcium matrix (new bone).

The mesenchymal stem cells within bone marrow have the potential to become the all important osteoblasts.  They can also become macrophages.  Meteabolic signaling guides what will happen.  Too much inflammation promotes macrophage Type of white blood cell designed to "eat up" debris and pathogens. It also stimulates various cells to respond to pathogens. formation and a lack of osteoblasts relative to too many osteoclasts Type of bone cell that removes old, damaged bone by the process bone resorption., in turn promoting bone loss.  Nutrients that encourage osteoblast formation are highly desireable for bone health.  This study shows that Cissus quadrangularis¹ not only helps mesenchymal stem cells turn into osteoblasts but that it also helps stimulate the production of more mesenchymal stem cells (which can then turn into more osteoblasts).  This herb contains highly bioactive regeneration properties for bone.

The researchers concluded that “Cissus quadrangularis¹ stimulates osteoblastogenesis and can be used as preventive/ alternative natural medicine for bone diseases such as osteoporosis.”