Can Pantethine Help Repair the Brain?

Tuesday, April 08, 2008  -  Byron Richards, CCN

French scientists have just reported that brain-derived neurotrophic factor (BDNF) can initiate the repair of brain1 networks that have been damaged.  This finding has far-ranging implications for mood, cognitive function, and recovery from significant problems involving the loss of neurological function such as a stroke.

BDNF is a growth factor for nerves, supporting the survival of existing neurons and helping to stimulate stem cells to make new ones – including new connections.  Both the nerve-transmitting cells and the glial cells of the brain secrete BDNF.  The new French study shows that BDNF is required for the repair of damaged nerve networks in the brain.  Stress lowers BDNF levels, exercise improves BDNF levels.  Compensating for stress and maintaining a positive mood is associated with maintaining an adequate supply of BDNF.

Pantethine may be an ideal nutrient to support BDNF function.  As a stress-busting nutrient it supports the adrenal glands as well as overall energy production.  One study explains that pantethine2 is ideally suited as a BDNF-stimulating nutrient.  Pantethine is metabolized to cysteamine, a compound now proven to boost BDNF function.  This is great news since pantethine has been in use as a dietary supplement for some time with no significant side effects or risks of any kind.

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Referenced Studies:
  1. ^ BDNF, A Key to Repairing and Maintaining Your Brain  Brain  Willson ML, McElnea C, Mariani J, Lohof AM, Sherrard RM.
  2. ^ Pantethine Helps Your Brain  Med Hypotheses.   Tsai SJ.

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