Bacopa – A Calming Nutrient that Boosts Cognitive Function

Monday, November 15, 2010
Byron J. Richards, Board Certified Clinical Nutritionist

Bacopa monniera is a traditional Ayurvedic herb used for centuries as a memory enhancing, anti-inflammatory, analgesic, and relaxant. Its unique combination of memory/cognitive performance boosting function along with a calming effect make it an ideal nutrient to help maintain composure while enhancing cognitive function.

Bacopa has been shown in animal studies to reduce both anxiety and depression1.  Partly this is due to balancing function of seratonin, dopamine, and noradnrealine and partly due to reducing the high levels of cortisol2.  Earlier animal studies also prove the ability of the herb to help tolerate stress and have a more balanced or adapted response to that stress.  The newest animal study shows that Bacopa enhances antioxidant function4 in the brain and reduces free radical damage in brain synapses, which supports better brain plasticity.  This study also proved Bacopa helped boost choline nerve transmission, which is associated with memory and cognitive performance.  Another study has shown that Bacopa can maintain cognitive function even in a low oxygen brain situation5.

In order to keep your brain running smoothly it is vital to have a baseline of calmness in your head, something you could also refer to as your natural brakes.  GABA is a relaxing neurotransmitter but it is often lacking under chronic stress and there are literally fewer GABA receptors that function – in turn making a person feel hyper, anxious, and/or too wound up.  As it turns out Bacopa is able to increase the number of GABA receptors6, a highly useful attribute. Bacopa also interacts with serotonin receptors in a way that smoothes out serotonin function7, a feature that is likely to be mood elevating. 

Bacopa has been shown in human clinical trials to boost memory and cognitive function8.  Australian researchers demonstrated this fact in a 90 day double blind study.  In healthy human subjects Bacopa was found to boost higher cognitive function and learning9.  A 12-week study in patients with age-associated memory impairment10 found that Bacopa significantly improved mental control, logical memory, digit forward, digit backward, visual reproduction and paired associate learning.

Bacopa is yet one more nutrient with brain enhancing attributes.  Its unique combination of supporting a calmer mood while boosting performance is going to help many people.

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Referenced Studies:
  1. ^ Bacopa Helps Anxiety and Depression in Mice  Indian J Exp Biol.  Chatterjee M, Verma P, Palit G.
  2. ^ Bacopa Balances Neurotransmitters and Cortisol  J Ethnopharmacol.   Sheikh N, Ahmad A, Siripurapu KB, Kuchibhotla VK, Singh S, Palit G.
  3. ^ Bacopa as a Stress-Related Adaptogen  Pharmacol Biochem Behav.  Rai D, Bhatia G, Palit G, Pal R, Singh S, Singh HK.
  4. ^ Bacopa Boosts Brain Antioxidant Status  Phytomedicine.   Department of Biochemistry and Nutrition, Central Food Technological Research Institute (Council of Scientific and Industrial Research), Mysore 570020, Karnataka, India.
  5. ^ Bacopa Offsets Low Oxygen Brain Impairment  Neurobiol Dis.   Hota SK, Barhwal K, Baitharu I, Prasad D, Singh SB, Ilavazhagan G.
  6. ^ Bacopa Increases GABA Receptor Functionality  Neurochem Res.  Mathew J, Gangadharan G, Kuruvilla KP, Paulose CS.
  7. ^ Bacopa Balances Seratonin Function  Epilepsy Behav.  Krishnakumar A, Nandhu MS, Paulose CS.
  8. ^ Bacopa Boosts Memory and Cognitive Function  Phytother Res  Stough C, Downey LA, Lloyd J, Silber B, Redman S, Hutchison C, Wesnes K, Nathan PJ.
  9. ^ Bacopa Boosts Learning  Psychopharmacology (Berl)  Stough C, Lloyd J, Clarke J, Downey LA, Hutchison CW, Rodgers T, Nathan PJ.
  10. ^ Bacopa Helps Offset Age-Associated memory Impairment  Indian J Psychiatry.   Raghav S, Singh H, Dalal PK, Srivastava JS, Asthana OP.

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